Editor, Editors, USER, admin, Bureaucrats, Check users, dev, editor, founder, Interface administrators, oversight, Suppressors, Administrators, translator
10,784
edits
Line 79: | Line 79: | ||
We are obviously in front of a series of topics that deserve adequate discussion because they concern clinical diagnostics. | We are obviously in front of a series of topics that deserve adequate discussion because they concern clinical diagnostics. | ||
Unlike formal languages used in mathematics, logic, and computer programming – characterized by artificial systems of signs governed by strict syntactic and semantic rules – most scientific languages evolve as an extension of natural language, enriching it with a set of technical terms. Medical language falls into this intermediate category: it arises from the expansion of everyday language by incorporating specific terminologies such as "neuropathic pain," "Temporomandibular Disorders," "demyelination," "allodynia," etc. This evolution does not involve the adoption of syntax or semantics distinct from those of the natural language from which it derives. Take, for example, the term "disease" in the context of patient Mary Poppins: a key word in medicine, essential for nosology, research, and clinical practice. Although it represents a fundamental concept in the field, its definition remains remarkably vague and not fully outlined. This ambiguity underscores the intrinsic complexity of medical language, which, despite being enriched with technical terminology, maintains the flexible and sometimes indeterminate characteristics of the natural language from which it originates. | |||
The exact meaning of the term "disease" eludes unanimous understanding, primarily interesting some philosophers of medicine, while most professionals in the field seem unconcerned with its precise definition. The fundamental question is whether the concept of "disease" should be associated with the subject or patient in individual terms, or whether it should refer to the System, that is, the living organism as a whole. This raises a further question: is it possible that a patient, who is not considered sick at time <math>t_n</math>, might actually coexist with a system that was already in a state of structural damage at an earlier moment, indicated as <math>t_{i,-1}</math>? | The exact meaning of the term "disease" eludes unanimous understanding, primarily interesting some philosophers of medicine, while most professionals in the field seem unconcerned with its precise definition. The fundamental question is whether the concept of "disease" should be associated with the subject or patient in individual terms, or whether it should refer to the System, that is, the living organism as a whole. This raises a further question: is it possible that a patient, who is not considered sick at time <math>t_n</math>, might actually coexist with a system that was already in a state of structural damage at an earlier moment, indicated as <math>t_{i,-1}</math>? | ||
This reflection leads to deep discussions on the dynamic nature of health and disease, proposing that disease should not be seen simply as an instantaneous state or a static condition, but as an evolutionary process, influenced by temporal factors and the interaction between different biological and pathological systems within the organism. This perspective requires a more sophisticated and probably quantitative interpretation of health, taking into account the temporal variations and dynamics between various biological and pathological systems. | This reflection leads to deep discussions on the dynamic nature of health and disease, proposing that disease should not be seen simply as an instantaneous state or a static condition, but as an evolutionary process, influenced by temporal factors and the interaction between different biological and pathological systems within the organism. This perspective requires a more sophisticated and probably quantitative interpretation of health, taking into account the temporal variations and dynamics between various biological and pathological systems.<blockquote>The use of the term "language without semantics," treated as if it were irrelevant or devoid of consequences, and its derivatives share the same lack of semantic clarity. This statement underscores a deep criticism of the assumption that language can exist in a purely structural or formal form, lacking semantic content that defines its meaning. In this way, the essential interdependence between semantics and language for understanding and effective communication is highlighted.''<ref>{{cita libro | ||
|autore=Sadegh-Zadeh Kazem | |autore=Sadegh-Zadeh Kazem | ||
|titolo=Handbook of Analytic Philosophy of Medicine | |titolo=Handbook of Analytic Philosophy of Medicine | ||
Line 98: | Line 98: | ||
;In short, | ;In short, | ||
The question of whether the patient, identified as Mary Poppins, is suffering from a pathology, or if it is her masticatory system exhibiting pathological symptoms, calls for a detailed analysis from a medical standpoint. The distinction between an individual disease and a dysfunction of a complex system like the masticatory system requires a holistic approach that considers the interrelations between the various anatomical and functional components involved. | |||
Medically, the condition could be interpreted as a pathology of the "System," that is, of the masticatory system as a whole. This system is comprised of multiple subsystems, including sensory receptors, both peripheral and central nervous tissue, jaw bones, teeth, tongue, and skin, each playing a critical role in the harmonious functioning of the entire system. A disorder in any of these components can therefore negatively affect the health of the masticatory system as a whole. | |||
Alternatively, the issue could be considered as a specific pathology of the "organ," in this context, the temporomandibular joint (TMJ), which plays a crucial role in mastication and phonation. Dysfunctions or pathologies of the TMJ can lead to complex symptoms that affect not only masticatory functionality but also the patient's quality of life, highlighting the importance of accurate diagnosis and targeted therapeutic approach. | |||
This discussion emphasizes how the ambiguities and limitations of natural language can complicate communication and understanding in the medical field, especially when attempting to describe and diagnose complex conditions. The use of precise medical terminology, along with the analysis of specific clinical cases, thus becomes essential to overcoming these challenges, facilitating clear dialogue and a better understanding of pathologies within the medical community. | |||
Line 110: | Line 113: | ||
</center> | </center> | ||
<center><gallery widths="350" heights="282" perrow="2" mode="slideshow"> | <center><gallery widths="350" heights="282" perrow="2" mode="slideshow"> | ||
File:Spasmo emimasticatorio.jpg|'''Figure 1:''' | File:Spasmo emimasticatorio.jpg|'''Figure 1:''' Representation of a patient complaining of "orofacial pain" on the right side of the face. | ||
File:Spasmo emimasticatorio ATM.jpg|'''Figure 2:''' | File:Spasmo emimasticatorio ATM.jpg|'''Figure 2:''' Stratigraphy of the patient's TMJ showing condylar flattening and the presence of osteophytes. | ||
File:Atm1 sclerodermia.jpg|'''Figure 3:''' Computed tomography of the TMJ | File:Atm1 sclerodermia.jpg|'''Figure 3:''' Computed tomography of the TMJ corroborating the stratigraphy findings shown in Figure 2. | ||
</gallery></center> | </gallery></center> | ||
== | ==Understanding of Medical Terminology== | ||
The Cambridge Dictionary | Exploring what "meaning" actually signifies enters us into a complex and multifaceted territory. The Cambridge Dictionary defines it as "what something expresses or represents."<ref>[https://dictionary.cambridge.org/dictionary/english/meaning Cambridge Dictionary online]</ref>However, this explanation, intuitive as it may be, leaves the question open since the understanding of "meaning" remains broad and not universally agreed upon. Various theories, each with their strengths and weaknesses, seek to address this question, leading to heated debates without a definitive answer.<ref>{{cita libro | ||
| autore = Blouw P | | autore = Blouw P | ||
| autore2 = Eliasmith C | | autore2 = Eliasmith C | ||
Line 144: | Line 145: | ||
| oaf = <!-- qualsiasi valore --> | | oaf = <!-- qualsiasi valore --> | ||
| PMID = | | PMID = | ||
}}</ref>. | }}</ref>. | ||
Traditionally, a term is considered a linguistic label representing an object, whether concrete or abstract. In this model, the term acts as an intermediary between language and the object it represents, as in the case of the word "apple," which evokes the image of the fruit known to everyone, regardless of their culture or age. However, terms like "orofacial pain" acquire different meanings depending on the context: for a neurologist, for a dentist, or for Mary Poppins herself, the meaning will vary considerably, reflecting different perspectives and knowledge bases. | |||
These expressions do not derive their meaning merely from representing something "out there" in the world, but rather from how they interact with other terms within their specific world or context. For Mary Poppins, pain takes on a particular meaning in relation to her personal experience and consciousness, independent of any quantifiable external expression such as attempting to assign it a value on a scale from 0 to 10, which may prove to be meaningless without an internal or normalized context. | |||
Similarly, a neurologist will interpret "pain in the right half of the face" based solely on his professional context, involving concepts like synapses, axons, ion channels, and action potentials. Conversely, a dentist will frame the meaning through a lens focused on teeth, the temporomandibular joint, masticatory muscles, and occlusion, demonstrating how meaning is intrinsically linked to the reference context. | |||
----Considering concepts is crucial in formulating a "differential diagnosis," as their misunderstanding can lead to clinical errors. It is therefore essential to explore the modern philosophy of "Meaning," introduced by Gottlob Frege,<ref>[[:wikipedia:Gottlob_Frege|Wikipedia entry]]</ref> which articulates the meaning of a term through the notions of "extension" and "intension." | |||
The concept | The "extension" of a concept includes all entities that share a certain characteristic, while "intension" refers to a set of attributes that outline that idea. Taking "pain" as an example, this term is generically applied to a wide range of human experiences, showing high extension but low intension. However, analyzing specific pain in contexts such as dental implants, inflammatory dental pulpitis, and neuropathic pain (atypical odontalgia),<ref>{{cita libro | ||
| autore = Porporatti AL | | autore = Porporatti AL | ||
| autore2 = Bonjardim LR | | autore2 = Bonjardim LR | ||
Line 171: | Line 169: | ||
| oaf = <!-- qualsiasi valore --> | | oaf = <!-- qualsiasi valore --> | ||
| PMID = 28118417 | | PMID = 28118417 | ||
}}</ref> we | }}</ref> we observe that: | ||
The | * The increase in mechanical and sensory perception threshold follows the activation of C fibers. | ||
* In cases of atypical odontalgia, somatosensory abnormalities such as allodynia, decreased mechanical perception, and reduced pain modulation emerge. | |||
* After the insertion of an implant, no significant somatosensory alterations are noted, although mild pain in the affected area is reported. | |||
* In general, "pain" has a wide extension and limited intension, but focusing on specific types of pain, we notice that greater intension leads to a reduction in extension. | |||
The "intension" of a concept indicates the distinctive aspects that separate it from others, reducing the concept's extension as the specificity of the intension increases. This allows us to distinguish, for example, TMJ pain from neuropathic pain. | |||
In conclusion, the meaning of a term in a given language can be considered as an ordered pair of extension and intension, within a "context." | |||
Specifically, in the dental context, "pain in the right half of the face" embraces a wide extension and an intension delineated by clinical characteristics and radiological or EMG investigations. In the neurological context, however, such pain is associated with an extension and intension defined by specific clinical and diagnostic parameters. | |||
This | This analysis highlights the vulnerability of medical language to causes of semantic and contextual ambiguity, showing how terms such as "nOP" or "TMD" can assume markedly different meanings depending on the context.<ref>{{cita libro | ||
| autore = Jääskeläinen SK | | autore = Jääskeläinen SK | ||
| titolo = Differential Diagnosis of Chronic Neuropathic Orofacial Pain: Role of Clinical Neurophysiology | | titolo = Differential Diagnosis of Chronic Neuropathic Orofacial Pain: Role of Clinical Neurophysiology | ||
Line 200: | Line 193: | ||
| oaf = <!-- qualsiasi valore --> | | oaf = <!-- qualsiasi valore --> | ||
| PMID = 31688325 | | PMID = 31688325 | ||
}}</ref> | }}</ref> | ||
---- | |||
==Ambiguity and Vagueness== | ==Ambiguity and Vagueness== | ||
Beyond the specific language used, the meaning of a medical term is strongly influenced by its originating context, which can lead to phenomena of "ambiguity" or "polysemy." A term is considered ambiguous or polysemic when it has more than one meaning. Linguistics and philosophy have paid considerable attention to these phenomena of ambiguity and vagueness;<ref>{{cita libro | |||
| autore = Schick F | | autore = Schick F | ||
| titolo = Ambiguity and Logic | | titolo = Ambiguity and Logic | ||
Line 247: | Line 241: | ||
| oaf = <!-- qualsiasi valore --> | | oaf = <!-- qualsiasi valore --> | ||
| PMID = | | PMID = | ||
}}</ref> | }}</ref>however, despite the negative impact that ambiguity and vagueness can have on adherence to and implementation of Clinical Practice Guidelines (CPGs),<ref>{{cita libro | ||
| autore = Codish S | | autore = Codish S | ||
| autore2 = Shiffman RN | | autore2 = Shiffman RN | ||
Line 263: | Line 257: | ||
| LCCN = | | LCCN = | ||
| OCLC = | | OCLC = | ||
}}</ref> | }}</ref> these concepts have not yet been fully investigated and distinguished in the medical context. | ||
Doctors' | Doctors' interpretations of vague medical terms can vary significantly,<ref>{{cita libro | ||
| autore = Kong A | | autore = Kong A | ||
| autore2 = Barnett GO | | autore2 = Barnett GO | ||
Line 283: | Line 277: | ||
| LCCN = | | LCCN = | ||
| OCLC = | | OCLC = | ||
}}</ref> | }}</ref>leading to less uniformity and greater variations in clinical practices compared to CPGs. Ambiguity is classified into syntactic, semantic, and pragmatic.<ref>{{cita libro | ||
| autore = Bemmel J | | autore = Bemmel J | ||
| autore2 = Musen MA | | autore2 = Musen MA | ||
Line 297: | Line 291: | ||
| oaf = <!-- qualsiasi valore --> | | oaf = <!-- qualsiasi valore --> | ||
| PMID = | | PMID = | ||
}}</ref> | }}</ref> | ||
As previously mentioned, a simple linguistic expression like the one referring to Mary Poppins can acquire at least three different meanings depending on the context. The ambiguity and vagueness associated with the term "orofacial pain" can thus become a source of diagnostic errors, highlighting a certain inefficiency of medical linguistic logic in decoding the "machine message" transmitted by the System in real-time. | |||
We delve deeper into this fascinating topic of "encrypted machine language," from which the subsequent chapters will develop. | |||
The term "orofacial pain" does not gain its meaning so much from its purest lexical expression as from the context in which it manifests, evoking a wide range of clinical domains, related symptoms, and interactions with other neuromotor systems, the trigeminal nerve, dental districts, etc. This machine language does not translate directly into verbal language but into an encrypted code based on its own alphabet, which must be deciphered to be converted into natural language. The focus then shifts to the linguistic logic employed to decode this message. To better illustrate this concept, let's consider some practical examples. | |||
{{q2|<!--93-->Doc, 10 years ago I started with a widespread discomfort in the jaw, including episodes of bruxism; these worsened so much that I was accusing ‘diffuse facial pain’, in particular in the area of the right ‘TMJ’ with noises in the movements mandibular.<br><!--94-->During this period, ‘vesicular lesions’ formed on my skin, which were more evident in the right half of my face.<br>In this period, however, the pain became more intense and intermittent|}} | Imagine that Mary Poppins complains of "orofacial pain," thus communicating her condition to the referring healthcare providers: | ||
----{{q2|<!--93-->Doc, 10 years ago I started with a widespread discomfort in the jaw, including episodes of bruxism; these worsened so much that I was accusing ‘diffuse facial pain’, in particular in the area of the right ‘TMJ’ with noises in the movements mandibular.<br><!--94-->During this period, ‘vesicular lesions’ formed on my skin, which were more evident in the right half of my face.<br>In this period, however, the pain became more intense and intermittent|}} | |||
The healthcare | The healthcare provider, whether a dermatologist, dentist, or neurologist, picks up certain verbal messages in Mary Poppins' dialogue, such as "widespread facial pain" or "TMJ" or "vesicular lesion," and establishes a series of hypothetical diagnostic conclusions that have nothing to do with encrypted language. | ||
However, in this context, we should move away from patterns and preconceived opinions to better understand the concept of "encrypted language." Let's assume, then, that the System is generating and sending the following encrypted message, for example: "Ephaptic." | |||
Now, what | Now, what relation does "Ephaptic" have with nOP or TMD? | ||
Nothing and everything, as we will better | Nothing and everything, as we will see better at the end of the chapters on the logic of medical language; we will then devote time to the concepts of cryptography and decryption. Perhaps we've heard about them in spy movies or in information security, but they are also important in medicine, as you will see. | ||
==Encryption== | ==Encryption== | ||
Let | Let's take as an example a common encryption and decryption platform. In the following example, we will illustrate the results of an Italian platform, but we could choose any platform, as the conceptual results do not change: | ||
We type our clear message; the machine converts it into something unreadable, but anyone who knows the "code" will be able to understand it. | |||
Let's assume, then, that the same happens when the brain sends a message in its machine language, made of wave trains, ion field packets, and so on; and that this carries a message to be decrypted, such as "Ephaptic." | |||
This message from the Central Nervous System must first be translated into verbal language, to allow the patient to give meaning to the linguistic expression and the doctor to interpret the verbal message. However, in this process, the machine message is polluted by the linguistic expression: both by the patient, who is unable to convert the encrypted message into the exact meaning (epistemic vagueness), and by the doctor, who is conditioned by the specific context of his specialization. | |||
The patient, in fact, by reporting symptoms of orofacial pain in the region of the temporomandibular joint, virtually combines the set of extension and intension into a diagnostic concept that allows the dentist to formulate the diagnosis of orofacial pain from temporomandibular disorders (TMD). | |||
Very often, the message remains encrypted at least until the system is damaged to such an extent that signs and clinical symptoms so obvious emerge to facilitate diagnosis. | |||
Understanding how encryption works is quite simple (go to the decryption platform, choose and try): | |||
# Choose an encryption key from those selected; | |||
# Type a word; | |||
# Obtain a code corresponding to the chosen key and the typed word. For example, if we enter the word 'Ephaptic' into the platform's encryption system, we will get an encrypted code in the three different contexts (patient, dentist, and neurologist) that correspond to the three different algorithmic keys indicated by the program; for instance, key A corresponds to the patient's algorithm, key B to the dental context, and key C to the neurological context. | |||
In the case of the patient, for example, by typing "Ephaptic" and using the A key, the "machine" will return a code like: | |||
<math>133755457655037A | |||
</math> | |||
The key can be defined as "Real Context." | |||
---- | |||
Let us continue with our example: | |||
Let us take a common encryption and decryption platform. In the following example we will report the results of an Italian platform but we can choose any platform because the results conceptually do not change: | |||
{{q2|<!--117-->Why do you say that the patient's "key" is defined as the REAL one?|<!--118-->difficult answer, but please observe the Gate Control phenomenon and you will understand}} | {{q2|<!--117-->Why do you say that the patient's "key" is defined as the REAL one?|<!--118-->difficult answer, but please observe the Gate Control phenomenon and you will understand}} |
edits