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Difference between revisions of "7° Klinischer Fall: Hirnstammneoplasie bei orofazialen Schmerzen"

7° Klinischer Fall: Hirnstammneoplasie bei orofazialen Schmerzen (view source)

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File:Assiografia dx modificata.jpeg|'''Abbildung 1:''' Rechtes konsuläres paraokklusales axiografisches Nachzeichnen: a) Zentrum der Scharnierachse, b) Orbitalebeneachse, c) prothetisches Nachzeichnen, d) medioprothetisches Nachzeichnen, e) medioprothetischer Kauzyklusbereich, f) lateroprothetischer Kauzyklusbereich, g) lateroprothetische Rücklinie, h) konsuläre Scharnierachse in maximaler Interkuspidation.
File:Assiografia dx modificata.jpeg|'''Abbildung 1:''' Rechtes konsuläres paraokklusales axiografisches Nachzeichnen: a) Zentrum der Scharnierachse, b) Orbitalebeneachse, c) prothetisches Nachzeichnen, d) medioprothetisches Nachzeichnen, e) medioprothetischer Kauzyklusbereich, f) lateroprothetischer Kauzyklusbereich, g) lateroprothetische Rücklinie, h) konsuläre Scharnierachse in maximaler Interkuspidation.
File:Assiografia sn.jpg|</math> and are represented with a ma Rechte konsulare paraokklusale axiografische Aufzeichnung: a) Drehachsezentrum, b) Orbitale Achsenebene, c) protrusive Aufzeichnung, d) mediotrusive Aufzeichnung, e) mediotrusiver kaubewegungsbereich, f) laterotrusiver kaubewegungsbereich, g) laterotrusive rücklinie.
File:Assiografia sn.jpg|'''Abbildung 2:''' Rechte konsulare paraokklusale axiografische Nachverfolgung: a) Scharnierachsenmitte, b) Orbitale Achsenebene, c) protrusive Nachverfolgung, d) mediotrusive Nachverfolgung, e) mediotrusiver Kieferzyklusbereich, f) laterotrusiver Kieferzyklusbereich, g) laterotrusive Rückenlinie.
File:Frisardi Gianni 0001.bmp.png|n often happen that some tests give a
File:Frisardi Gianni 0001.bmp.png|'''Abbildung 2:''' Interferenzielle EMG der rechten (oben) und linken (unten) Masseter-Muskeln. Amplitude 200μV pro Teilung, Zeitteilung 100 msec.
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The sentence {{:F:Imo}} (dental context) with a number <math>n\geq1</math> of other logically compatible statements <math>(\delta_1,\delta_2,.....\delta_n \ )</math> determine the union and coherence between them <math>\Im_o\cup\{\delta_1,\delta_2.....\delta_n\}</math> and are represented with a mathematical formalism to facilitate the diagnostic dialectic in the following way <math>\Im_o\cup\{\delta_1,\delta_2.....\delta_n\}\rightarrow
Der Satz {{:F:Imo}} (im zahnärztlichen Kontext) zusammen mit einer Anzahl <math>n\geq1</math> anderer logisch kompatibler Aussagen <math>(\delta_1,\delta_2,.....\delta_n \ )</math> bestimmen die Vereinigung und Kohärenz zwischen ihnen <math>\Im_o\cup\{\delta_1,\delta_2.....\delta_n\}</math> und werden mit einem mathematischen Formalismus dargestellt, um die diagnostische Dialektik auf folgende Weise <math>\Im_o\cup\{\delta_1,\delta_2.....\delta_n\}\rightarrow
\Im_o\cup\{0,0.....0\}=0</math> which represents the average of the individual assertions reported. The average has been designed because it can often happen that some tests give answers with negative reporting to which to give the value <math>\delta_n=0</math>. The result in this case is <math>\delta_n=0</math> and contextually derives the coherent affirmation of the sentence <math>\Im_o</math> in which it is argued that the symptomatology of the 'Capsaicin' patient is not determined by the presence of a TMDs.          
\Im_o\cup\{0,0.....0\}=0</math> zu erleichtern, was den Durchschnitt der einzelnen gemeldeten Behauptungen repräsentiert. Der Durchschnitt wurde gewählt, weil es häufig vorkommen kann, dass einige Tests negative Antworten liefern, denen der Wert <math>\delta_n=0</math> zugeordnet wird. Das Ergebnis ist in diesem Fall <math>\delta_n=0</math>, was kontextuell die kohärente Bestätigung des Satzes <math>\Im_o</math> ableitet, in dem argumentiert wird, dass die Symptomatik des 'Capsaicin'-Patienten nicht durch das Vorhandensein von TMDs bestimmt wird.                                  


In the ''neurological context'' we will therefore have the following sentences and assertions to which we obviously give, as for the dental context, a numerical value to facilitate the treatment and that is <math>\gamma_n=[0|1]</math> where i<math>\gamma_n=0</math> indicates 'normality' and <math>\gamma_n=1</math>'abnormality' and therefore positivity of the report:       
In the ''neurological context'' we will therefore have the following sentences and assertions to which we obviously give, as for the dental context, a numerical value to facilitate the treatment and that is <math>\gamma_n=[0|1]</math> where i<math>\gamma_n=0</math> indicates 'normality' and <math>\gamma_n=1</math>'abnormality' and therefore positivity of the report:       
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The interaction between neurons and immune cells is a well-known phenomenon.<ref>Jacobson A, Yang D, Vella M, Chiu IM (May 2021). "The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes". ''Mucosal Immunology''. '''14''' (3): 555–565. doi:10.1038/s41385-020-00368-1. PMC 8075967. <nowiki>PMID 33542493</nowiki>.</ref> TRPV1 plays its role, too, in neuroinflammation by being expressed in both neurons and immune cells. Significant importance should be given to the confirmed expression of TRPV1 in microglia and astrocytes, cells found in the vicinity of neurons. The neuro-immune axis is the site of production of neuroinflammatory molecules and receptors that interact between the two systems and ensure a complex response to external stimuli (or to the body's own pathologies). TRPV1 is said to contribute to microglia autophagy through its Ca<sup>2+</sup> signaling, which leads to mitochondria-induced cell death. Basically, TRPV1 is a pro-apoptotic element.  
The interaction between neurons and immune cells is a well-known phenomenon.<ref>Jacobson A, Yang D, Vella M, Chiu IM (May 2021). "The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes". ''Mucosal Immunology''. '''14''' (3): 555–565. doi:10.1038/s41385-020-00368-1. PMC 8075967. <nowiki>PMID 33542493</nowiki>.</ref> TRPV1 plays its role, too, in neuroinflammation by being expressed in both neurons and immune cells. Significant importance should be given to the confirmed expression of TRPV1 in microglia and astrocytes, cells found in the vicinity of neurons. The neuro-immune axis is the site of production of neuroinflammatory molecules and receptors that interact between the two systems and ensure a complex response to external stimuli (or to the body's own pathologies). TRPV1 is said to contribute to microglia autophagy through its Ca<sup>2+</sup> signaling, which leads to mitochondria-induced cell death. Basically, TRPV1 is a pro-apoptotic element.  


===== Ligands=====
=====Ligands=====


=====Antagonists=====
=====Antagonists=====
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