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'''Abstract:''' This article explores the application and mechanisms of Transcranial Magnetic Stimulation (TMS) in studying neuroplasticity, particularly in the context of motor cortex reorganization after stroke. TMS, a non-invasive technique that uses magnetic fields to stimulate specific brain regions, allows researchers to map motor cortical areas and assess neuronal excitability. The study emphasizes that motor representations in the cortex are distributed over a network of primary and secondary motor areas, with overlapping motor maps that govern various muscle groups. | |||
Research on neuroplasticity, particularly after stroke, reveals that the brain undergoes continuous reorganization, challenging the long-held belief that the adult brain is static. Following damage, areas adjacent to the injury often compensate for lost function, a phenomenon observed in both animal models and human studies. Motor and somatosensory evoked potentials, alongside magnetic stimulation, have shown to be useful in predicting functional recovery and assessing the degree of cortical reorganization. | |||
The article discusses the importance of peripheral inputs for maintaining normal cortical organization and how their deprivation leads to significant reorganization of motor and sensory areas. Neuroplasticity mechanisms, such as unmasking pre-existing connections, synaptic modifications, and axonal sprouting, are explored in detail. Clinical findings indicate that motor recovery after stroke is associated with changes in cortical excitability and motor output, with notable interhemispheric asymmetry during the recovery process. | |||
The conclusion highlights that motor recovery is not solely dependent on lesion resolution but involves dynamic cortical reorganization. The integration of neurophysiological tools like TMS with imaging techniques provides deeper insights into the mechanisms underlying recovery, underscoring the need for personalized rehabilitation approaches. | |||
[[File:MagStim.jpeg|thumb|'''Figure 1:''' Magnetic Stimulation]] | [[File:MagStim.jpeg|thumb|'''Figure 1:''' Magnetic Stimulation]] |
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