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| '''Patient:''' "I appreciate your concern, doctor, but really, I have no problems chewing or swallowing. And as for bruxism or postural issues, I don't suffer from them. I'm also very physically active. For me, undergoing treatment that I don't feel is necessary would be excessive." | | '''Patient:''' "I appreciate your concern, doctor, but really, I have no problems chewing or swallowing. And as for bruxism or postural issues, I don't suffer from them. I'm also very physically active. For me, undergoing treatment that I don't feel is necessary would be excessive." |
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| '''Dentist:''' "I understand your position. It's crucial that you feel comfortable with any decision made regarding your health. My role is to inform you about potential long-term implications and available treatment options. If you ever change your mind or need further information, know that I'm here to assist you." | | '''Dentist:''' "I understand your position. It's crucial that you feel comfortable with any decision made regarding your health. My role is to inform you about potential long-term implications and available treatment options. If you ever change your mind or need further information, know that I'm here to assist you."{{apm}}[[Category:Introduction]] |
| ----The situation becomes particularly critical when we consider the patient's verbal language regarding their chewing functionality. This can be misleading, as it may not reflect a detailed understanding of the pathophysiology of the occlusal state. On the contrary, it could paradoxically indicate an intact system if interpreted through a "machine language" converted into verbal terms. In this impasse, neither the patient nor the observer (dentist) can assert with certainty the presence of an actual "Malocclusion."
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| In this context, the reference to the American Statistical Association's critique entitled "Statistical inference in the 21st century: A World Beyond p < 0.05" becomes relevant, as it invites the researcher to navigate uncertainty with sensitivity, reflexivity, openness, and modesty in assertions.<ref name="wasser" /> This stance paves the way for interdisciplinarity as a key to addressing such complex issues.
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| The interdisciplinary approach becomes crucial in interpreting the biological phenomenon of "Malocclusion" through a stochastic mindset, which will be explored in more detail later.
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| A stochastic observer might note that, at time <math>T_n </math>, there is a low probability that the patient is in a state of occlusal disease, given their expression of optimal psychophysical well-being. This leads to the conclusion that occlusal discrepancy does not necessarily entail a neuromuscular and psychophysical functional disorder. Therefore, the masticatory system should not be normalized solely to occlusion but requires a broader understanding that includes the Trigeminal Nervous System.
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| To assess the integrity of the patient's Trigeminal Nervous System in the presence of "malocclusion," specific electrophysiological tests were performed. The results of these tests, shown in Figures 1b, 1c, and 1d (with explanations in the captions), should be interpreted as a "Conceptual Rationale" within the context of the "Malocclusion" issue. These introductory data reveal an apparent discrepancy between the occlusal state, which traditionally might be considered pathological, and the neurophysiological data demonstrating perfect synchronization and symmetry of trigeminal reflexes.
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| <gallery mode="slideshow">
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| File:Bilateral Electric Transcranial Stimulation.jpg|'''Figure 1b:''' Figure 1b displays the results of a motor-evoked potential test obtained through transcranial electrical stimulation of the trigeminal nerve roots. The focus is on structural symmetry, which was calculated by comparing the peak-to-peak amplitude of the evoked potentials in the right masseter muscle (upper trace) and left masseter muscle (lower trace).
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| File:Jaw Jerk .jpg|'''Figura 1c:''' This figure shows the jaw reflex evoked by percussion of the chin with a piezoelectric neurological hammer. Once again, what stands out is the observed functional symmetry, highlighted by the analysis of peak-to-peak amplitude in the right and left masseter muscles. Functional symmetry in a malocclusion condition suggests that reflexive responses of the masticatory system can remain effectively balanced despite occlusal discrepancies. This further reinforces the argument that a diagnosis of malocclusion does not necessarily translate into manifest neuromuscular dysfunctions, and that the integrity of the masticatory system can be maintained.
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| File:Mechanic Silent Period.jpg|'''Figura 1d:''' Illustrates the evoked mechanical silent period elicited by percussion of the chin with a triggered neurological hammer. This type of measurement focuses on the integral area of the right and left masseter muscles, and what emerges prominently is the functional symmetry between the two sides. The presence of this symmetry underscores that, despite the malocclusion condition, neuromuscular dynamics, specifically in terms of reflex inhibition after stimulation, are maintained in a balanced equilibrium.
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| </gallery>
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| Through the examination of these electrophysiological data – Figures 1b, 1c, and now 1d – a picture emerges that challenges conventional interpretations of malocclusion and its clinical implications. The observed functional symmetry in these measurements indicates that the approach to diagnosing and treating malocclusions could significantly benefit from a broader evaluation, including detailed analysis of neuromuscular function. These results emphasize the importance of an interdisciplinary and integrated diagnostic and therapeutic model that goes beyond simply correcting occlusal discrepancies to include an overall assessment of the well-being of the masticatory system and, by extension, the patient.
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| <blockquote>''Occlusal Dismorphisms and Not Malocclusion ......which, as we will see shortly, is an entirely different matter.''</blockquote>
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| ==Conclusion==
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| Before proceeding with any conclusion, it is crucial to clarify some fundamental concepts that will be explored in more detail in specific chapters of Masticationpedia.
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| The masticatory system should be interpreted as a "Complex System"<ref>https://en.wikipedia.org/wiki/Complex_system</ref> rather than being reduced to a simple biomechanical mechanism focused solely on dental occlusion. From this perspective, occlusion represents only one of the numerous subsets operating within a broader context. These subsets include periodontal receptors, neuromuscular spindles, motor unit recruitment, the central nervous system, and the temporomandibular joint. The interaction among these components gives rise to what we can define as "Emergent Behavior", specifically masticatory behavior.
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| This notion implies that the emergent behavior of the system cannot be interpreted or predicted solely based on objective data extracted from a single subset. Instead, it is necessary to assess the integrity of the system as a whole before proceeding with an analytical segmentation for a detailed description. There are significant intellectual and scientific movements addressing this challenge. A notable example is found in the work of Kazem Sadegh-Zadeh, "Handbook of Analytic Philosophy of Medicine".<ref>{{cita libro
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| | autore = Sadegh-Zadeh Kazem
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| | titolo = Handbook of Analytic Philosophy of Medicine
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| | url = https://link.springer.com/book/10.1007/978-94-007-2260-6
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| | volume =
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| | opera =
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| | anno = 2012
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| | editore = Springer
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| | città = Dordrecht
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| | ISBN = 978-94-007-2259-0
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| | LCCN =
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| | DOI = 10.1007/978-94-007-2260-6
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| | OCLC =
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| }}.</ref>
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| In light of these considerations, the discussion on the case at hand follows the following linguistic logic: the various subsets of the masticatory system, such as teeth, occlusion, temporomandibular joints, and muscles, exhibit "Coherence" with the Central Trigeminal Nervous System (as illustrated in Figures 1b, 1c, and 1d). Consequently, the use of the term "Malocclusion" is inadequate; it would be more appropriate to speak of "Occlusal Dysmorphisms".
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| :
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| :{{q2|The proposition to consider the masticatory system as a "Complex System" does not imply the denial of existing rehabilitative therapies, such as prosthetic, orthodontic, and orthognathic treatments aimed at correcting masticatory dysfunctions. On the contrary, this innovative approach aims to reintegrate and enrich medical knowledge in rehabilitative dental disciplines, providing an alternative perspective to the scientific reductionism that tends to interpret biological phenomena in an overly deterministic manner.|}}Adopting a perspective that transcends the boundaries of individual specializations, as highlighted by the importance of interdisciplinarity, is crucial for enriching diagnostic and therapeutic models in dentistry. This approach is exemplified in the clinical case of a patient treated with the OrthoNeuroGnathodontic methodology, which provides an integrated overview of the masticatory system, combining aesthetic and functional-neurophysiological aspects. This interdisciplinary model aims to achieve "Occlusal Stability" and prevent "Relapses," particularly relevant in orthodontic and orthognathic treatments.<ref>Essam Ahmed Al-Moraissi, Larry M Wolford. Is Counterclockwise Rotation of the Maxillomandibular Complex Stable Compared With Clockwise Rotation in the Correction of Dentofacial Deformities? A Systematic Review and Meta-AnalysisJ Oral Maxillofac Surg.. 2016 Oct;74(10):2066.e1-2066.e12.doi: 10.1016/j.joms.2016.06.001. Epub 2016 Jun 11.
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| </ref><ref>J Hoffmannová, R Foltán, M Vlk, K Klíma, G Pavlíková, O Bulik. Factors affecting the stability of bilateral sagittal split osteotomy of a mandible.Prague Med Rep. 2008;109(4):286-97.
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| </ref> This perspective does not aim to eliminate existing rehabilitative practices but, on the contrary, seeks to enrich and restore value to dental rehabilitative disciplines, while offering an alternative to the reductionistic view that often dominates the interpretation of biological phenomena. In this context, an "Extraordinary Science" is introduced, which leverages interdisciplinarity to expand the boundaries of medical knowledge and practice. In the meantime, let us take a reflective pause thanks to a provocative question from our curious companion, Linus Sapiens, the yellow figure positioned on the left. This allegorical interaction invites us to consider the complexity of the masticatory system with a sense of wonder and curiosity, emphasizing the importance of remaining open to new perspectives and innovative solutions in the field of dentistry.
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| [[File:Question_2.jpg|left|150px]]
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| {{qnq|What do we mean by “Complex Systems” when we are talking about masticatory functions?}}
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