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== Abstract == | |||
The text begins by introducing the concept of orofacial pain and temporomandibular disorders (TMD), citing a comprehensive review by Martina Ferrillo et al. on pain management for temporomandibular sensitization. The common association between orofacial pain and other symptoms such as headaches and neck pain is emphasized, suggesting that these conditions may mutually influence each other. | |||
Correlations between TMD and other disorders: The relationships between TMD and other conditions like headaches and neck pain are explored, highlighting the possible causes and mechanism of symptom transmission. The importance of considering the possibility of other pathologies when evaluating symptoms related to TMD is emphasized. | |||
Bayesian approach and comparison with frequentist statistics: The use of Bayesian statistics in the context of TMD and severe headaches is discussed, comparing it with frequentist statistics and discussing their respective limitations and advantages. | |||
Quantum-like modeling and biological interpretation: The concept of quantum modeling in biological systems is explored, and the difference between a classical probabilistic model and a quantum one is discussed, emphasizing the implications for interpreting biological data. | |||
Conclusions: The text concludes by emphasizing the complexity of TMD and orofacial pain and the need for a critical and objective approach to diagnosis and treatment. It promises to present two clinical cases that will illustrate key points for differentiating orofacial pain from TMD and oromandibular dystonia. | |||
{{ArtBy|autore=Gianni Frisardi}} | {{ArtBy|autore=Gianni Frisardi}} | ||
=== Introduction === | ===Introduction === | ||
As usual in the presentation of new sections of specific chapters, it is advisable to introduce recent and documented references on the subject which in this case is 'Orofacial Pain' and Temporomandibular Disorders. In this sense we can partially report a brief introduction by Martina Ferrillo et al.<ref>Martina Ferrillo, Amerigo Giudice, Nicola Marotta, Francesco Fortunato,Daniela Di Venere,Antonio Ammendolia, Pietro Fiore, and Alessandro de Sire. Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review. Int J Mol Sci. 2022 Oct; 23(20): 12164. Published online 2022 Oct 12. doi: 10.3390/ijms232012164. PMCID: PMC9602546. PMID: 36293017</ref> on which we will make the first conceptual reflections reported by our thoughtful Linus before proceeding to the presentation of the clinical cases. | As usual in the presentation of new sections of specific chapters, it is advisable to introduce recent and documented references on the subject which in this case is 'Orofacial Pain' and Temporomandibular Disorders. In this sense we can partially report a brief introduction by Martina Ferrillo et al.<ref>Martina Ferrillo, Amerigo Giudice, Nicola Marotta, Francesco Fortunato,Daniela Di Venere,Antonio Ammendolia, Pietro Fiore, and Alessandro de Sire. Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review. Int J Mol Sci. 2022 Oct; 23(20): 12164. Published online 2022 Oct 12. doi: 10.3390/ijms232012164. PMCID: PMC9602546. PMID: 36293017</ref> on which we will make the first conceptual reflections reported by our thoughtful Linus before proceeding to the presentation of the clinical cases. | ||
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</blockquote>{{q2|Could an asymptomatic person be ill?|difficult question that needs a complex answer ... have patience and you'll see}} | </blockquote>{{q2|Could an asymptomatic person be ill?|difficult question that needs a complex answer ... have patience and you'll see}} | ||
=== Conclusion === | ===Conclusion=== | ||
Orofacial pain together with temporomandibular disorders are very complex pathophysiological phenomena which, despite the spread of clinical protocols available to the clinician, must be considered objectively but critically. If we consider the clinical cases already presented and the limitations described regarding the measurement error, the machine language logic with the code decryption process and the limitations of the Bayesian statistical procedures we can realize as a differential diagnosis between Orofacial Pain from Temporomandibular Disorders and Orofacial Pain from Oromandibular Dystonia is not quite so appreciable. Therefore, we will present two clinical cases that will highlight the essential methodological and clinical points to perform a rapid and detailed differential diagnosis between Orofacial Pain due to Temporomandibular Disorders and Orofacial Pain due to Oromandibular Dystonia{{Bib}} | Orofacial pain together with temporomandibular disorders are very complex pathophysiological phenomena which, despite the spread of clinical protocols available to the clinician, must be considered objectively but critically. If we consider the clinical cases already presented and the limitations described regarding the measurement error, the machine language logic with the code decryption process and the limitations of the Bayesian statistical procedures we can realize as a differential diagnosis between Orofacial Pain from Temporomandibular Disorders and Orofacial Pain from Oromandibular Dystonia is not quite so appreciable. Therefore, we will present two clinical cases that will highlight the essential methodological and clinical points to perform a rapid and detailed differential diagnosis between Orofacial Pain due to Temporomandibular Disorders and Orofacial Pain due to Oromandibular Dystonia{{Bib}} |
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