Difference between revisions of "Encrypted code: Ephaptic transmission"

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== Conclusion ==
== Conclusion ==
As demonstrated, the definition of 'Emasticatory spasm' in our patient Mary Poppins was not a clinically simple process, however, considering the topics presented in the previous chapters of Masticationpedia we have at least three elements of support available:
As demonstrated, the definition of Hemasticatory spasm in our patient Mary Poppins was not a clinically simple process, however, considering the topics presented in the previous chapters of Masticationpedia we have at least three elements of support available:


# A vision of 'Quantum Probability' of physical-chemical phenomena in complex biological systems which will be discussed extensively in the specific chapters.
# A vision of 'Quantum Probability' of physical-chemical phenomena in complex biological systems which will be discussed extensively in the specific chapters.
# A more formal and less vague language than the natural language that directs the diagnostic analysis to the first input node of the 'CNN' through the '<math>\tau</math> Coherence Demarcator' described in the chapter '[[1° Clinical case: Hemimasticatory spasm - en|1st Clinical case: Hemimasticatory spasm]]'
# A more formal and less vague language than the natural language that directs the diagnostic analysis to the first input node of the 'CNN' through the '<math>\tau</math> Coherence Demarcator' described in the chapter '[[1° Clinical case: Hemimasticatory spasm - en|1st Clinical case: Hemimasticatory spasm]]'
# The 'CNN' process which, being managed and guided exclusively by the clinician, becomes an essential means for the definitive diagnosis.
# The 'CNN' process which, being managed and guided exclusively by the clinician, becomes an essential means for the definitive diagnosis.
The 'CNN', in fact, is the result of a profound cognitive process that is performed on each step of the analysis in which the clinician weighs his intuitions, clarifies his doubts, evaluates the reports, considers the contexts and advances step by step confronting the result of the answer coming from the database which in our case is Pubmed which substantially represents the current level of basic knowledge <math>KB_t</math>at question time and the <math>KB_c</math> in the broadest specialist contexts.  
The 'CNN', in fact, is the result of a profound cognitive process that is performed on each step of the analysis in which, the clinician weighs his intuitions, clarifies his doubts, evaluates the reports, considers the contexts and advances step by step confronting the result of the answer coming from the Pubmed database.  Substantially the Pubmed database represents the current level of basic knowledge <math>KB_t</math> at question time and the <math>KB_c</math> in the broadest specialist contexts.  


A linear representation of this cognitive process labeled as <math>RNC_1 </math>with the necessary annotations it could be the following:<blockquote>
A linear representation of this cognitive process labeled as <math>CNN_1 </math> with the necessary annotations it could be the following:<blockquote>


<math>RNC_1=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+&size=200 Trigeminal Reflex],[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+&size=200 Demyelinating neuropathy], [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+latency Latency],[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+latency+amplitude Amplitude],[https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex '''H-reflex'''], [https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex+masseter+muscle&size=200 Masseter muscle], [https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex+masseter+muscle+temporal+muscle&size=200 Temporal muscle], [https://pubmed.ncbi.nlm.nih.gov/31164256/ Heteronymous H reflex in temporal muscle as sign of hyperexcitability in ALS patients],[https://pubmed.ncbi.nlm.nih.gov/?term=Temporal+muscle+abnormal+response&size=200 Temporal muscle abnormal response]<math>)</math><math>\longrightarrow</math>[https://pubmed.ncbi.nlm.nih.gov/27072096/ '''Ephaptic transmission is the origin of the abnormal muscle response seen in hemifacial spasm''']</blockquote>There are essentially two annotations to note: the first is the mandatory identification of the initialization input that derives from the context chosen through the '<math>\tau</math> Coherence Demarcator' and the second the order of the cognitively selected keywords.
<math>CNN_1=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+&size=200 Trigeminal Reflex],[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+&size=200 Demyelinating neuropathy], [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+latency Latency],[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+demyelinating+neuropathy+latency+amplitude Amplitude],[https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex '''H-reflex'''], [https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex+masseter+muscle&size=200 Masseter muscle], [https://pubmed.ncbi.nlm.nih.gov/?term=h+reflex+masseter+muscle+temporal+muscle&size=200 Temporal muscle], [https://pubmed.ncbi.nlm.nih.gov/31164256/ Heteronymous H reflex in temporal muscle as sign of hyperexcitability in ALS patients],[https://pubmed.ncbi.nlm.nih.gov/?term=Temporal+muscle+abnormal+response&size=200 Temporal muscle abnormal response]<math>)</math><math>\longrightarrow</math>[https://pubmed.ncbi.nlm.nih.gov/27072096/ '''Ephaptic transmission is the origin of the abnormal muscle response seen in hemifacial spasm''']</blockquote>There are essentially two annotations to observe: the first is the mandatory identification of the 'Initialization command' that derives from the context chosen through the '<math>\tau</math> Coherence Demarcator' and the second the order of the cognitively selected keywords.


{{Q2|In fact, what happens to the 'RNC' if we consider the dental context by inserting the keyword 'Temporomandibular Disorders' as an initialization input, keeping everything else unchanged?}}
{{Q2|In fact, what happens to the 'CNN' if we consider the dental context by inserting the keyword 'Temporomandibular Disorders' as an initialization input, keeping everything else unchanged?}}


By marking the network as <math>RNC_2 </math> with a dental initialization input ( Temporomandibular disorders) as follows:
By marking the network as <math>CNN_2 </math> with a dental initialization input ( Temporomandibular disorders) as follows:


<blockquote><math>RNC_2=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+&filter=dates.1970-2022 Temporomandibular Disorders],[https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+trigeminal+reflex&filter=dates.1970-2022 Trigeminal reflex],  [https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+trigeminal+reflex+Demyelinatying+neuropathy&filter=dates.1970-2022 Demyelinaying neuropathy], [https://pubmed.ncbi.nlm.nih.gov/1520092/ Latency<math>\longrightarrow</math>'''Side asymmetry of the jaw jerk in human craniomandibular dysfunction''']</blockquote>The message is corrupted, as explained above regarding the mathematical formula, as the initialization command input ( Tempormandibular disorders) directs the network for a set of data, no less than 20,514, which lose connections with a part of subsets. While maintaining the rest of the CNN similar to the previous one (neurological context) the network stops at the keyword 'latency' showing only one scientific article which obviously concerns the latency of the jaw jerk but not related to neuropathic disorders. (figure 5) The error in the choice of the initialization command input of the <math>RNC </math> process not only corrupts the message to be decrypted but renders vain all the upstream work of analysis of the clinical assertions discussed in the chapters of language logic.   
<blockquote><math>CNN_2=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+&filter=dates.1970-2022 Temporomandibular Disorders],[https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+trigeminal+reflex&filter=dates.1970-2022 Trigeminal reflex],  [https://pubmed.ncbi.nlm.nih.gov/?term=Temporomandibular+disorders+trigeminal+reflex+Demyelinatying+neuropathy&filter=dates.1970-2022 Demyelinaying neuropathy], [https://pubmed.ncbi.nlm.nih.gov/1520092/ Latency<math>\longrightarrow</math>'''Side asymmetry of the jaw jerk in human craniomandibular dysfunction''']</blockquote>The message is corrupted, as explained above regarding the mathematical formula, as the 'Initialization command input' ( Tempormandibular disorders) directs the network for a set of data, no less than 20,514, which lose connections with a part of subsets. While maintaining the rest of the CNN similar to the previous one (neurological context) the network stops at the keyword 'latency'. In fact, only one scientific article was extracted and obviously concerns the latency of the jaw jerk but is not related to neuropathic disorders. (figure 5) The error, in the choice of the initialization command input of the <math>CNN </math> process not only corrupts the message to be decrypted but renders vain all the upstream work of analysis of the clinical assertions discussed in the chapters of language logic.   


[[File:Temporomandibular disorders trigeminal reflex demyelinatying neuropathy latency amplitude.jpg|center|thumb|'''Figure 5:''' Ending the 'CNN' loop with an initialization input of 'Tempororomandibular Disorders']]   
[[File:Temporomandibular disorders trigeminal reflex demyelinatying neuropathy latency amplitude.jpg|center|thumb|'''Figure 5:''' Ending the 'CNN' loop with an initialization input of 'Tempororomandibular Disorders']]   


However, changing the order of the keywords in an exact cognitive path such as the neurological one essentially returns the same results as the previous one provided that the initialization command input is perfectly centred, as can be seen in the following simulation labeled with <math>RNC_3 </math>:  
However, changing the order of the keywords in an exact cognitive path such as the neurological one, essentially, returns the same results as the previous one provided that the initialization command input is perfectly focalized, as can be seen in the following simulation labeled with <math>CNN_3 </math>:  


<math>RNC_3=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+ Trigeminal reflex], [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude amplitude] [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency latency] [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency+Demyelinating+neuropathy demyelinating neuropathy] <math>\longrightarrow</math> [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency+Demyelinating+neuropathy '''H-reflex''']................   
<math>CNN_3=\sum ( </math>[https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+ Trigeminal reflex], [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude amplitude] [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency latency] [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency+Demyelinating+neuropathy demyelinating neuropathy] <math>\longrightarrow</math> [https://pubmed.ncbi.nlm.nih.gov/?term=trigeminal+reflex+amplitude+latency+Demyelinating+neuropathy '''H-reflex''']................   


and reconnects to the previous one until closing in the output 'Ephaptic transmission is the origin of the abnormal muscle response seen in hemifacial spasm' (Figure 6)   
and reconnects to the previous one until closing in the output 'Ephaptic transmission is the origin of the abnormal muscle response seen in hemifacial spasm' (Figure 6)   
[[File:Ephaptic trasmission.jpg|center|thumb|'''Figure 6:''' Process of 'CNN' with order of keywords changed. ]]
[[File:Ephaptic trasmission.jpg|center|thumb|'''Figure 6:''' Process of 'CNN' with order of keywords changed. ]]
Note that if this chapter had been published in an impacted international scientific journal (Inpact Factor) the <math>KB_t</math>and contextually a hypothetical 'machine learning' would have been enriched with a new content or that of the diagnosis of 'Hemimasticatory spasm' defined following the electrophysiological method of the heteronymous H-reflex. This conclusion will come in handy when we repeat the same procedure for other clinical cases in which the <math>KB_t</math>is updated to the database output.    
Note that if this chapter had been published in an impacted international scientific journal (Impact Factor) the <math>KB_t</math> and contextually a hypothetical 'machine learning' would have been enriched with a new content or that of the diagnosis of 'Hemimasticatory spasm' defined following the electrophysiological method of the heteronymous H-reflex. This conclusion will come in handy when we repeat the same procedure for other clinical cases in which the <math>KB_t</math> is updated to the database output.          
 
To learn more about the methodological description of the 'Heteronimous H-Reflex', the reader is invited to follow [[Appendix 1]].     


=== Bibliography ===
=== Bibliography ===
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<references />
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