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[[File:Finite Elements - electric field within the intracranial brain tissue - FEM.jpg|thumb|'''Figure 1:''' The figure shows the arrangement of the electrodes on the skull and the distribution of electric fields inside the intracranial brain tissue]] | [[File:Finite Elements - electric field within the intracranial brain tissue - FEM.jpg|thumb|'''Figure 1:''' The figure shows the arrangement of the electrodes on the skull and the distribution of electric fields inside the intracranial brain tissue]] | ||
Considering the safety limitations,<ref>IEC60601-2-40 (1998) Medical electrical equipment: Particular requirements for the safety of electromyographs and evoked response equipment.</ref> we computed the energy delivered for each single pulse in our application through this formula: <math>E=P\cdot\Delta T=R\cdot I^2\cdot \Delta T=2.5 mJ</math> per pulse. Since 2 stimulators were used, the limits were ten times lower than those stated in the IEC regulation. | Considering the safety limitations,<ref>IEC60601-2-40 (1998) Medical electrical equipment: Particular requirements for the safety of electromyographs and evoked response equipment.</ref> we computed the energy delivered for each single pulse in our application through this formula: <math>E=P\cdot\Delta T=R\cdot I^2\cdot \Delta T=2.5 mJ</math> per pulse. | ||
The electrodes were arranged as described below. A common anode to the 2 electrostimulators was placed at the vertex, while a cathode electrode was placed on each side at 12-13 cm along the line joining the vertex to the acoustic meatus in the parietal region. The electrical stimulus consisted of a square wave lasting 250 μsec at a voltage of ≅ 300 V and maximum current of 100 mA. | |||
Since 2 stimulators were used, the limits were ten times lower than those stated in the IEC regulation. | |||
The electrodes were then arranged as described below. A common anode to the 2 electrostimulators was placed at the vertex, while a cathode electrode was placed on each side at 12-13 cm along the line joining the vertex to the acoustic meatus in the parietal region. The electrical stimulus consisted of a square wave lasting 250 μsec at a voltage of ≅ 300 V and maximum current of 100 mA. | |||
To show the distribution of the electric field inside the intracranial brain tissue we report in Figure 1 an analysis performed through a generic Finite Element process (FE, SimNibs method), only as a descriptive model (data not reported).<ref name=":2">Windhoff M, Opitz A, Thielscher A (2013) [https://pubmed.ncbi.nlm.nih.gov/22109746/ Electric field calculations in brain stimulation based on finite elements: an optimized processing pipeline for the generation and usage of accurate individual head models.] Hum Brain Mapp 34: 923-935.</ref> | To show the distribution of the electric field inside the intracranial brain tissue we report in Figure 1 an analysis performed through a generic Finite Element process (FE, SimNibs method), only as a descriptive model (data not reported).<ref name=":2">Windhoff M, Opitz A, Thielscher A (2013) [https://pubmed.ncbi.nlm.nih.gov/22109746/ Electric field calculations in brain stimulation based on finite elements: an optimized processing pipeline for the generation and usage of accurate individual head models.] Hum Brain Mapp 34: 923-935.</ref> |
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