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• 17:18, 17 October 2024 Gianni talk contribs created page Pain Pathophysiology (Created page with "The use of pain-relieving substances dates back to the dawn of humanity. In particular, in animistic cultures, psychotropic substances were used for shamanic practices to seek a state of ecstasy that brought them closer to the primary source of life and knowledge. This laid the foundations for a proto-medicine whose primary goal was the relief of pain caused by wounds or illness. Pain, like illness, was often considered the result of a curse from demons or hostile deitie...")