adenome pleomorphe
Pleomorphic adenome is a common benign neoplasm of the salivary glands characterized by neoplastic proliferation of epithelial (ductal) cells together with myoepithelial components, with malignant potential. It is the most common type of salivary gland tumor and the most common parotid gland tumor. It derives its name from architectural pleomorphism (variable appearance) seen under the light microscope. It is also known as a "mixed tumor, salive gland type", which refers to its dual origin from epithelial and myoepithelial elements in contrast to its pleomorphic appearance.
Diagnosis of salivary gland tumors uses tissue samples and radiographic studies. Tissue sampling procedures include fine needle aspiration (FNA) and core needle biopsy (needle larger than FNA). Both procedures can be performed on an outpatient basis. Imaging techniques for salivary gland tumors include ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). CT allows direct bilateral visualization of the tumor of the salivary glands and provides information on the overall size and tissue invasion. The CT is excellent for the demonstration of the invasion of the ocean. MRI provides superior delineation of soft tissue, such as perineural invasion, compared to CT alone, as well described by Mehmet Koyuncu et al. al.[1]
This last observation is very important because an invasion of the tumor of the nervous tissues in the infratemporal fossa cannot be excluded and precisely because of the complexity of the disease we report a study by Rosalie A Machado et al. al.[2]This can be further explored in the Masticationpedia subchapter 'Intermittent facial spasms as a presenting sign of a recurrent pleomorphic adenoma', in which the authors confirm that to date the development of facial spasms has not been reported in parotid neoplasms. The most common etiologies of hemifacial spasm are vascular compression of the facial nerve ipsilateral to the cerebellopontine angle (defined as primary or idiopathic) (62%), hereditary (2%), secondary to Bell's palsy or facial nerve injury (17%) and hemifacial spasm mimics (psychogenic, tics, dystonia, myoclonus, myochemia, myoarrythmias, and hemimasticatory spasm) (17%).
- ↑ Mehmet Koyuncu, Teoman Seşen, Hüseyin Akan, Ahmet A Ismailoglu, Yücel Tanyeri, Atilla Tekat, Recep Unal, Lütfi Incesu. Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors.Otolaryngol Head Neck Surg. 2003 Dec;129(6):726-32.doi: 10.1016/j.otohns.2003.07.009.
- ↑ . 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86. Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken. Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma. World J Clin Oncol. 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86.