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=== Adénome pléomorphe ===
=== adenome pleomorphe ===
[[File:Cytopathology of pleomorphic adenoma.png|thumb|Figure 4 : Examen histologique d'un adénome pléomorphe de [[wikipedia:Pleomorphic_adenoma|Wikipedia]] ]]
[[File:Cytopathology of pleomorphic adenoma.png|thumb|Figure 4 : Histological examination of a pleomorphic adenome [[wikipedia:Pleomorphic_adenoma|Wikipedia]] ]]
L'adénome pleomórfico es una neoplasia benigna común de las glándulas salivales caracterizada por la proliferación neoplásica de células epiteliales (ductales) junto con componentes mioepiteliales, con potencial maligno. Es el tipo más común de tumor de la glándula salive y el tumor de la glándula parótida más común. Deriva su nombre del pleomorfismo arquitectónico (aspecto variable) visto bajo el microscopio óptico. También se le conoce como "tumor mixto, tipo glándula salive", lo que hace referencia a su origen dual a partir de elementos epiteliales y mioepiteliales en contraste con su aspecto pleomórfico.
Pleomorphic adenome is a common benign neoplasm of the salivary glands characterized by neoplastic proliferation of epithelial (ductal) cells together with myoepithelial components, with malignant potential. It is the most common type of salivary gland tumor and the most common parotid gland tumor. It derives its name from architectural pleomorphism (variable appearance) seen under the light microscope. It is also known as a "mixed tumor, salive gland type", which refers to its dual origin from epithelial and myoepithelial elements in contrast to its pleomorphic appearance.


El diagnóstico de los tumores de las glándulas salivales utiliza muestras de tejido y estudios radiográficos. Los procedimientos de muestreo de tejido incluyen aspiración con aguja fina (FNA) y biopsia con aguja gruesa (aguja más grande que FNA). Ambos procedimientos se pueden realizar de forma ambulatoria. Las técnicas de diagnóstico por imágenes para los tumores de las glándulas salivales incluyen ultrasonido, tomografía computarizada (TC) e imágenes por resonancia magnética (IRM). La TC permet la visualisation directe bilatérale de la tumeur des glandes salivaires et apporte des informations sur le tamaño général et l'invasion du tejido. La TC est excellente pour la démonstration de l'invasion de l'océan. La RM proporciona una delineación superior de los tejidos blandos, como la invasión perineural, en comparación con la TC sola, como bien lo describen Mehmet Koyuncu et al.<ref>Mehmet Koyuncu, Teoman Seşen, Hüseyin Akan, Ahmet A Ismailoglu, Yücel Tanyeri, Atilla Tekat, Recep Unal, Lütfi Incesu. [https://pubmed.ncbi.nlm.nih.gov/14663442/ Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors].Otolaryngol Head Neck Surg. 2003 Dec;129(6):726-32.doi: 10.1016/j.otohns.2003.07.009.
Diagnosis of salivary gland tumors uses tissue samples and radiographic studies. Tissue sampling procedures include fine needle aspiration (FNA) and core needle biopsy (needle larger than FNA). Both procedures can be performed on an outpatient basis. Imaging techniques for salivary gland tumors include ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). CT allows direct bilateral visualization of the tumor of the salivary glands and provides information on the overall size and tissue invasion. The CT is excellent for the demonstration of the invasion of the ocean. MRI provides superior delineation of soft tissue, such as perineural invasion, compared to CT alone, as well described by Mehmet Koyuncu et al. al.<ref>Mehmet Koyuncu, Teoman Seşen, Hüseyin Akan, Ahmet A Ismailoglu, Yücel Tanyeri, Atilla Tekat, Recep Unal, Lütfi Incesu. [https://pubmed.ncbi.nlm.nih.gov/14663442/ Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors].Otolaryngol Head Neck Surg. 2003 Dec;129(6):726-32.doi: 10.1016/j.otohns.2003.07.009.
</ref><blockquote>Esta última observación es muy importante porque no se puede excluir una invasión del tumor de los tejidos nerviosos en la fosa infratemporal y precisamente por la complejidad de la enfermedad reportamos un trabajo de Rosalie A Machado et al.<ref>. 2017 Feb 10;8(1):86-90.
</ref><blockquote>This last observation is very important because an invasion of the tumor of the nervous tissues in the infratemporal fossa cannot be excluded and precisely because of the complexity of the disease we report a study by Rosalie A Machado et al. al.<ref>. 2017 Feb 10;8(1):86-90.


doi: 10.5306/wjco.v8.i1.86.
doi: 10.5306/wjco.v8.i1.86.


Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken. [https://pubmed.ncbi.nlm.nih.gov/28246588/ Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma.] World J Clin Oncol. 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86.
Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken. [https://pubmed.ncbi.nlm.nih.gov/28246588/ Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma.] World J Clin Oncol. 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86.
</ref>lo cual se puede profundizar en el subcapítulo de Masticationpedia 'Espasmos faciales intermitentes como signo de presentación de un adenoma pleomórfico recurrente' en el que los autores confirman que hasta la fecha no se ha reportado el desarrollo de espasmos faciales in neoplasias de parótida. Las etiologías más comunes del espasmo hémifacial son la compression vasculaire del nervio facial ipsilateral al ángulo pontocerebeloso (definida como primaria o idiopática) (62 %), hereditaria (2 %), secundaria a parálisis de Bell o lesión del nervio facial (17 %) y imitadores de spasmos hemifaciales (psicogénicos, tics, distonía, mioclonía, miochemia, mioarrtmias y spasmo hemimasticatorio) (17 %).</blockquote>
</ref>This can be further explored in the Masticationpedia subchapter 'Intermittent facial spasms as a presenting sign of a recurrent pleomorphic adenoma', in which the authors confirm that to date the development of facial spasms has not been reported in parotid neoplasms. The most common etiologies of hemifacial spasm are vascular compression of the facial nerve ipsilateral to the cerebellopontine angle (defined as primary or idiopathic) (62%), hereditary (2%), secondary to Bell's palsy or facial nerve injury (17%) and hemifacial spasm mimics (psychogenic, tics, dystonia, myoclonus, myochemia, myoarrythmias, and hemimasticatory spasm) (17%).</blockquote>

Revision as of 10:13, 1 May 2023

adenome pleomorphe

Figure 4 : Histological examination of a pleomorphic adenome Wikipedia

Pleomorphic adenome is a common benign neoplasm of the salivary glands characterized by neoplastic proliferation of epithelial (ductal) cells together with myoepithelial components, with malignant potential. It is the most common type of salivary gland tumor and the most common parotid gland tumor. It derives its name from architectural pleomorphism (variable appearance) seen under the light microscope. It is also known as a "mixed tumor, salive gland type", which refers to its dual origin from epithelial and myoepithelial elements in contrast to its pleomorphic appearance.

Diagnosis of salivary gland tumors uses tissue samples and radiographic studies. Tissue sampling procedures include fine needle aspiration (FNA) and core needle biopsy (needle larger than FNA). Both procedures can be performed on an outpatient basis. Imaging techniques for salivary gland tumors include ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI). CT allows direct bilateral visualization of the tumor of the salivary glands and provides information on the overall size and tissue invasion. The CT is excellent for the demonstration of the invasion of the ocean. MRI provides superior delineation of soft tissue, such as perineural invasion, compared to CT alone, as well described by Mehmet Koyuncu et al. al.[1]

This last observation is very important because an invasion of the tumor of the nervous tissues in the infratemporal fossa cannot be excluded and precisely because of the complexity of the disease we report a study by Rosalie A Machado et al. al.[2]This can be further explored in the Masticationpedia subchapter 'Intermittent facial spasms as a presenting sign of a recurrent pleomorphic adenoma', in which the authors confirm that to date the development of facial spasms has not been reported in parotid neoplasms. The most common etiologies of hemifacial spasm are vascular compression of the facial nerve ipsilateral to the cerebellopontine angle (defined as primary or idiopathic) (62%), hereditary (2%), secondary to Bell's palsy or facial nerve injury (17%) and hemifacial spasm mimics (psychogenic, tics, dystonia, myoclonus, myochemia, myoarrythmias, and hemimasticatory spasm) (17%).

  1. Mehmet Koyuncu, Teoman Seşen, Hüseyin Akan, Ahmet A Ismailoglu, Yücel Tanyeri, Atilla Tekat, Recep Unal, Lütfi Incesu. Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors.Otolaryngol Head Neck Surg. 2003 Dec;129(6):726-32.doi: 10.1016/j.otohns.2003.07.009.
  2. . 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86. Rosalie A Machado, Sami P Moubayed, Azita Khorsandi, Juan C Hernandez-Prera, Mark L Urken. Intermittent facial spasms as the presenting sign of a recurrent pleomorphic adenoma. World J Clin Oncol. 2017 Feb 10;8(1):86-90. doi: 10.5306/wjco.v8.i1.86.