Difference between revisions of "Complex Systems/pt"

  }}</ref>. <span lang="en" dir="ltr" class="mw-content-ltr">Hence, to describe the impaired function of the hippocampus in a reduced situation or abnorme asticatory function, the authors employed an animal model (mice) called ‘Molarless Senescence-Accelerated Prone’ (SAMP8) in order to make a parallelism on man</span>. <span lang="en" dir="ltr" class="mw-content-ltr">In SAMP8 mice, to which the occlusion was modified, increasing the occlusal vertical dimension of about 0.1 mm with dental materials showed that the occlusal disharmony disrupts learning and memory</span>. <span lang="en" dir="ltr" class="mw-content-ltr">These animals showed an age-dependent deficit in space learning at Morris’s water</span>. <ref>{{Cite book  

  }}</ref> <span lang="en" dir="ltr" class="mw-content-ltr">These changes in the catecolaminergic and serotonergic systems, induced by occlusal disharmonies, clearly affect the innervation of the hippocampus</span>. <span lang="en" dir="ltr" class="mw-content-ltr">The conditions of increasing the vertical dimension alter neurogenesis and lead to apoptosis in the ippocampal gyrus by decreasing the expression of the ippocampal brain derived from neurotrophic factors</span>: <span lang="en" dir="ltr" class="mw-content-ltr">all this could contribute to the changes in observed learning in animals with occlusal disharmony</span>.<ref name="MFCF" />